Vaker BRCA-mutaties bij mensen van Joodse komaf

Fred H. Menko, Efraim H. Rosenberg en Lizet E. van der Kolk*

BRCA mutations more frequent in people of Jewish ancestry

Three BRCA1/BRCA2 mutations occur more frequently in the Jewish population than in the general population. In Jewish patients with breast cancer about 10% of cases are caused by one of these mutations; consequently, all patients with breast cancer and who are of Jewish ancestry, or their healthy family members, are eligible for genetic testing.

Conflict of interest and financial support: none declared.