Systematische opsporing van infecties met Chlamydia trachomatis bij mannen en vrouwen zonder klachten in de huisartspraktijk met behulp van per post verstuurde urinemonsters

I.G.M. van Valkengoed, A.J.P. Boeke, A.J.C. van den Brule, S.A. Morré, J.H. Dekker, C.J.L.M. Meijer en J.Th.M. van Eijk

Systematic screening for asymptomatic Chlamydia trachomatis infections by home obtained mailed urine samples in men and women in general practice

To determine the prevalence and determinants of Chlamydia trachomatis (CT) infections among asymptomatic men and women in general practice. To determine participation rates in a systematic screening programme in general practice, using home obtained mailed urine samples.


Cross-sectional study.


In 15 general practices in Amsterdam, the Netherlands, a sample of 11,005 persons (5541 women and 5464 men), aged 15-40 were invited to send in a urine sample and a completed questionnaire by mail. The urine samples were tested using the ligase chain reaction for DNA amplification. Patients diagnosed with CT were treated and partner notification was performed.


33 of invited males (1809/5464) and 50 of females (2751/5541) sent in the study material. Older patients participated more frequently than younger patients. Participation rates among persons with a Dutch background were higher than rates among persons from other ethnic groups. In 42 men and 79 women a CT infection was identified (2.3 and 2.9 respectively). Infections were more prevalent in patients from Surinam and the Dutch Antilles and in the age category 21-25 years. Type of health insurance as a proxy measure of socioeconomic status was not an indicator of infection.


The participation in this systematic screening using mail-sent urine samples was 33 in men and 50 in women. The CT prevalences among asymptomatic men and women were 2.3 and 2.9 respectively.