Geïnfecteerde gewrichtsprothese

Stand van zaken
Henk Scheper, Marjan Wouthuyzen-Bakker, Karin Ellen Veldkamp, Robert J.P. van der Wal, H. Charles Vogely en Mark G.J. de Boer

Prosthetic joint infection

A prosthetic joint infection (PJI) is a serious complication that can lead to lengthy hospitalization, significant limitations in mobility, and a reduced quality of life.

For acute PJI, the aim is to cure the infection whilst retaining the prosthesis; this can be achieved by means of thorough surgical debridement, cleaning of the artificial material, replacement of exchangeable prosthesis parts and adjuvant antibiotic therapy.

In cases of chronic PJI, the prosthetic joint needs to be replaced.

For patients in whom surgery is not feasible, or who refuse surgical intervention, chronic suppressive antibiotic therapy can be applied if the infection persists.

In order to increase the likelihood of a favourable outcome, it is important to take a multidisciplinary approach.

Conflict of interest and financial support: none declared.