Diagnostiek en behandeling van het slokdarmcarcinoom in Nederland: veel variatie in de tweede lijn

To survey the diagnostic procedures and treatment strategies currently employed in hospitals for patients with oesophageal cancer.

Design

Questionnaire.

Method

A questionnaire was sent to all clinicians working in the field of gastroenterology in the Netherlands. This questionnaire focused on clinical preferences regarding diagnostic procedures and treatment strategies for oesophageal cancer. Also, six hypothetical patient vignettes were presented in order to investigate which factors affected choice of treatment, in particular surgical treatment.

Results

The response rate was 64 (426/667); 336 questionnaires were relevant to the investigation. Almost 90 of the clinicians treated fewer than 20 patients annually, usually in their own hospital. CT was the most frequently used staging procedure; endoscopic ultrasound was less frequently used (42 used it in less than half the patients). The treatment choice for the patient vignettes varied widely among clinicians. Factors influencing the choice to operate or not were: metastases, loco-regional tumour ingrowth, poor general health, and advanced age with 8, 22, 20, and 53, respectively, of the clinicians still considering surgery in the presence of one of these factors as opposed to 99 if none of these factors were present. Surgeons opted for operation more often than internists and gastroenterologists. Stent placement was the most frequently chosen method to palliate malignant dysphagia.

Conclusion

There is a wide variation in the use of diagnostic procedures and treatment strategies for patients with oesophageal cancer in the Netherlands. This stresses the need for scientifically based practice guidelines, taking into account specific patient and tumour characteristics.