Wat betekent ‘gevoelig’?

Three patients, a woman aged 36 and two men aged 38 and 25 years, who presented with signs of abdominal typhus, were treated with ciprofloxacin. Salmonella typhi was cultured from blood samples in the first patient, Salmonella paratyphi in the second and both bacteria in the third. According to the automated laboratory culture system, the culture results indicated that the bacteria were sensitive to ciprofloxacin. However, the response to treatment was insufficient in all three patients. According to the cut-off points for antibiotic sensitivity that automated systems use for Enterobacteriaceae, some Salmonellae may appear to be sensitive to ciprofloxacin, whereas in fact they are at least partially resistant. The European Committee on Antimicrobial Susceptibility Testing (EUCAST) has stated that Salmonella strains with a minimal inhibitory concentration of ciproflaxacin > 0.064 mg/l have a decreased clinical response to treatment.