Het effect van intraoperatieve hypotensie op herseninfarcten na chirurgie*

Objective

To study the effect of intraoperative hypotension on the occurrence of stroke following non-cardiac and non-neurosurgical procedures.

Design

Nested patient-control study.

Methods

From January 2002-June 2009, all patients at UMC Utrecht who had a stroke within 10 days of undergoing a non-cardiac or non-neurosurgical procedure were matched with 6 control patients of the same age who underwent the same procedure but had no stroke.

Results

A total of 42 patients who suffered postoperative stroke (0.09%) were included. After correction for potential confounders, the length of time that the mean blood pressure remained more than 30% lower than baseline was statistically significantly associated with the occurrence of a postoperative stroke.

Conclusion

Intraoperative hypotension may play a role in the development of postoperative ischaemic stroke.

Conflict of interest: none declared. Financial support: none declared.