Gentherapie in Nederland

- Extensive research is ongoing worldwide on the clinical utility of gene therapy, particularly for the treatment of cancer and genetic disorders.

- Two gene therapy products have already been approved recently in China.

- Clinical experience with gene therapy has also been accumulating in the Netherlands: over 200 Dutch patients have now been treated in clinical trials.

- Published results indicate that gene therapy is generally safe.

- Gene therapy appears to be effective for some genetic disorders, such as severe combined immune deficiency and haemophilia B.

- The efficacy of gene therapy, particularly in the treatment of cancer, appears to be limited up till now.

Ned Tijdschr Geneeskd. 2007;151:1975-80