Behandeling van infecties met zeer resistente bacteriën

The prevalence of carbapenemase-producing Enterobacteriaceae and multi-resistant Pseudomonas aeruginosa is increasing worldwide.

In the Netherlands, we are also confronted with infections with these highly resistant bacteria.

For the treatment of such infections, we rely on experiences from case reports and results of retrospective studies.

Trials of potential combination therapies are currently being set up or have just started.

No new classes of antibiotics are to be expected in the short term. New drugs are being sought mainly in existing classes and combinations of antibiotics.

In this article, we discuss currently available treatment options, including non-pharmacological treatments such as fecal transplantation.

Conflict of interest and financial support: none declared.