Een vrouw met unilateraal tepeleczeem

A 46-year-old woman presented with pain in her right hip and chest since 6 months. Physical examination showed an erythematosquamous lesion of the right nipple (3 x 4 cm), there were no lumps in either breast. This skin lesion had been present since 2 years. A biopsy with histopathological and immunohistochemical examination showed Paget’s disease. Mammography with biopsy and CT-scanning proved an invasive ductal carcinoma of the right mamma with ossal metastasis.