Een 35-jarige man met gynaecomastie als eerste symptoom van hyperthyreoïdie

- A 35-year-old man suffered painful bilateral gynaecomastia for 2 months due to serious Graves' hyperthyroidism. During treatment with propylthiouracil and levothyroxine, the plasma concentrations of thyroid hormone, sex hormones and sex hormone-binding globulin normalised and the gynaecomastia disappeared. Gynaecomastia occurs in 30 to 40 of men diagnosed with Graves’ hyperthyroidism. However, gynaecomastia as a presenting symptom of this autoimmune disease is uncommon.