Impulscontrolestoornis door gebruik van dopamineagonisten

There is an increasing awareness and growing scientific evidence that impulse control disorders (ICDs), including pathologic gambling and compulsive sexual behaviour, can occur as a complication of the use of dopamine agonists in Parkinson’s disease (PD), and also in Restless Legs syndrome. Risk factors to develop an ICD are: young age or early onset of Parkinson’s disease, impulsive or novelty-seeking personality features, family or personal history of alcoholism, impulse control disorder before onset of Parkinson’s disease, dopamine agonist therapy. It is important that both prescribing physicians and patients be aware that the use of dopamine agonists may lead to the development of an ICD. Clinicians should monitor patients for this adverse effect. Lacking established treatments for ICDs, clinical management should initially consist of lowering the dosage or discontinuation of dopamine agonist therapy.