Chemotherapie voor hersenmetastasen van carcinomen

– Three case histories are presented of patients with brain metastases from different kinds of carcinoma which showed objective responses to chemotherapy. These demonstrate that systemic chemotherapy is not only effective against systemic metastases but against brain metastases as well. At present, in the Antoni van Leeuwenhoek Huis chemotherapy is being used more regularly in patients with brain metastases from carcinoma, and preliminary results show objective responses in 8 of 11 patients. These results point out that more clinical studies are needed to determine the applicability of systemic chemotherapy in brain metastases, either as single treatment or combined with surgery or radiation.