Waarom adenocarcinoom van de slokdarm vaker voorkomt

• The incidence of oesophageal adenocarcinoma has increased rapidly over the past decades in the Western world.
• The prognosis is poor with a mean 5-year survival rate of 19% in the Netherlands.
• Important risk factors that might account for this rising incidence are reflux, obesity and the absence of Helicobacter pylori.
• Oesophageal adenocarcinoma is 9 times more likely in men than in women.
• The reason for this much higher incidence of adenocarcinoma in men is still unclear, but sex hormones may play a role.

Conflict of interest: none declared. Financial support: none declared.