Voorbijgaande cholelithiasis bij gebruik van ceftriaxon

– Two patients are described with biliary colic in association with treatment with the new cephalosporin antibiotic ceftriaxone. Ceftriaxone is excreted in high concentrations in bile and, especially when high doses are used, precipitation of ceftriaxone calcium may occur. Although the concretions formed disappear spontaneously after stopping ceftriaxone, colicky pains may ensue. Cholelithiasis in patients using ceftriaxone must not be treated surgically.