Kanalopathieën: genetische verklaring voor migraine en andere paroxismale neurologische aandoeningen

There is increasing evidence of involvement of genes coding for ion channels in the pathogenesis of paroxysmal neurological disorders.

Recently for instance, mutations in the calcium channel gene on chromosome 19 were identified in migraine, ataxia, and epilepsy.

With the current research into inherited ‘channelopathies’ a new approach has been established.

A better understanding of the pathophysiology of paroxysmal neurological disorders may lead to new therapeutic strategies.