Jobenguaan-131-therapie als eerste keus bij het niet gemetastaseerde neuroblastoom

¹³¹I-MIBG as the treatment of choice of non-metastasized neuroblastoma. – Three children with a localized pelvic neuroblastoma are presented. Because of progression and clinical signs of compression of adjacent structures therapy was necessary. Targeted radiotherapy with ¹³¹I-MIBG was used as the first mode of therapy. This new strategy proved to be feasible, effective and non-toxic. Application of ¹³¹I-MIBG as first-line therapy should be considered more often in neuroblastoma patients.