De eerste hersenoperaties in Nederland

The archives of the Association Dutch Journal of Medicine contain letters written between 1890 and 1893 in Utrecht from the psychiatrist and later professor of nervous diseases Dr. C. Winkler, to Dr. C.C. Delprat, general practitioner and lecturer in nervous diseases in Amsterdam; at the time Delprat was also editor-in-chief of the Journal. The letters contain some private comments about two of the first brain operations that were performed in the Netherlands, as well as about a new method to delineate the location of separate cerebral gyri under the skull. Winkler also formally reported the two case histories and the localisation method in the Journal . The main problem in these early brain operations was to locate the lesion purely on the basis of clinical features.