Twee patiënten met een CC9-intoxicatie

Background: Hexahydrocannabinol-C9 (CC9) is a novel synthetic cannabinoid with largely unknown toxicity and clinical effects.

Case description: We report two patients with CC9 intoxication presenting with atypical and prolonged symptoms, including profound somnolence, bradycardia, neuropsychiatric disturbances, and impaired mobility. Both patients experienced a protracted course lasting up to 90 hours.

Management: Treatment was primarily focused on symptom control in a low-stimulus environment. Close monitoring of respiratory function was essential in cases of profound sedation, while benzodiazepines were administered when severe agitation occurred. Activated charcoal combined with a laxative was used in one case and may have contributed to recovery by reducing intestinal reabsorption.

Conclusion: Clinicians should be alert to the atypical and prolonged course of intoxications caused by new synthetic cannabinoids such as CC9. Early recognition, multidisciplinary consultation, and supportive treatment in a low-stimulus environment are essential.

Conflict of interest and financial support: none declared.