Morfine geïndiceerd bij patiënten met astma cardiale?

Aanwijzingen voor negatieve effecten van morfine
Stand van zaken
30-11-2015
Thijs W.H. Flinsenberg, Joep van der Leeuw, Asaf Gafni, Antonie J.H.H.M. van Oostrom en Jeroen P.H. van Wijk

Is morphine indicated in patients with cardiac asthma? Indications for negative effects from the use of morphine

  • According to current Dutch and European guidelines, morphine has a place in the treatment of patients with cardiac asthma.
  • There are no studies showing an improvement in objective parameters with the use of morphine in patients with cardiac asthma.
  • Recent large retrospective cohort studies indicate an increased mortality risk among patients given morphine in the treatment of cardiac asthma, even after correction for confounders. In addition, morphine may be linked to an increased risk of intensive care unit admission.
  • Morphine should be used with caution in patients with cardiac asthma.

Conflict of interest and financial support: none declared.