Metabole botafwijkingen bij maag-, darm- en leverziekten

- Gastrointestinal and hepatic diseases are frequently associated with metabolic bone disorders, especially osteoporosis and osteomalacia.

- Malabsorption of vitamin D and calcium are important aetiological factors, although other factors may contribute, like the use of glucocorticosteroids in the treatment of inflammatory bowel disease.

- Treatment is first of all focused on correction of calcium and vitamin D deficiency.

- In severe osteoporosis additional treatment with bisfosfonates needs serious consideration.