Laparoscopische elektrocoagulatie van de ovaria voorafgaande aan in-vitrofertilisatie bij twee vrouwen met het polycysteus-ovariumsyndroom

- A 32-year-old woman with oligomenorrhoea/amenorrhoea and a 30-year-old woman with oligomenorrhoea as a result of the polycystic ovary syndrome (PCOS), with an active desire for children, were considered eligible for in-vitro fertilisation (IVF) because the semen of their partners was of inferior quality. However, the patients’ polycystic ovaries proved to be difficult to stimulate. There was either no response to stimulation with gonadotropins or an excessive response, as a result of which treatment had to be stopped prematurely. However, when laparoscopic ovarian electrocautery was done and a stimulation cycle was subsequently started, adequate and controlled stimulation of the ovaries turned out to be quite possible in both cases. Afterwards, a follicle aspiration could be performed with success and intracytoplasmic sperm injection (ICSI) was carried out. Embryo transfer resulted in pregnancy only in the first patient. This procedure, which has never been described before in the Dutch literature, might also be effective in other women with PCOS who are eligible for IVF.

Ned Tijdschr Geneeskd 2005;149:1350-2