Eradicatie van Helicobacter pylori mogelijk gevolgd door gastro-oesofageale refluxziekte

- Colonisation with Helicobacter pylori exerts several effects on the production of acid. The bacterium does not play a direct role in the pathogenesis of gastroesophageal reflux disease (GORD). Successful eradication of H. pylori in patients with ulcer disease appears to be followed by an increase in incidence of GORD. It has been postulated that the infection could protect against the development of GORD. H. pylori ulcers and gastritis should be treated by eradication therapy. It is unclear yet what is the best treatment in patients with H. pylori infection without an ulcus or gastritis.