Diagnostiek en behandeling van leveradenomen

• Hepatocellular adenomas are essentially benign tumours of the liver that occur mostly in women of reproductive age.
• The four different subtypes described, which can be distinguished both radiologically and histopathologically, are: steatotic, inflammatory, β-catenin mutated and unclassified adenomas. These subtypes differ in the risk of complications.
• Contrast-enhanced liver MRI is the best method for diagnostics and characterization of hepatocellular adenomas.
• Possible complications include bleeding, rupture, and malignant degeneration of the hepatocellular adenoma. These complications are rare in adenomas < 5 cm.
• Men with hepatocellular adenomas are at higher risk for malignant degeneration.
• In women, lifestyle changes (cessation of oral contraceptive and weight reduction) can cause regression of the adenoma, which can prevent the necessity for liver surgery.
• In pregnant women there is a risk of growth of hepatocellular adenoma. It is, therefore, it is recommended to check the tumour in pregnant women every 6-12 weeks using ultrasound.

Conflict of interest and financial support: none declared.