De 'polypil': geen effectieve strategie tegen hart- en vaatziekten

– The implementation of the intriguing concept of the polypill to prevent cardiovascular events remains doubtful due to a lack of evidence, expected adherence problems, the inevitable overtreatment and undertreatment of individuals, and potential side effects. Lifestyle changes and individual interventions are more preferable strategies.

Ned Tijdschr Geneeskd 2005;149:1741