De behandeling van malaria

Stand van zaken
11-06-2019
B. Jelle Visser, Marieke Bierhoff, Tom van Gool, Jarne M. van Hattem, Martin P. Grobusch en Michèle van Vugt

The treatment of malaria

  • In the Netherlands, approximately 200 to 300 patients are diagnosed with imported malaria every year.
  • The symptoms of malaria are non-specific.
  • The current gold standard for malaria diagnostics is to conduct a thick and thin blood smear. New diagnostic techniques are increasingly applied.
  • At present, the treatment of uncomplicated malaria consists of an artemisinin-based combination therapy (ACT). An alternative treatment for malaria caused by P. vivax,P. knowlesi,P. ovale and P. malariae in the Netherlands is chloroquine.
  • Severe malaria is treated with artesunate intravenously, followed by a full three-day course of oral ACT.
  • Uncomplicated malaria during pregnancy is treated with an ACT (e.g. artemether-lumefantrine) and severe malaria with artesunate intravenously, the latter followed by a full three-day course of oral ACT.
  • There is currently no malaria vaccine available for travellers.

Conflict of interest and financial support: none declared.