Chronische depersonalisatie na cannabisgebruik

- A 19-year-old patient had developed a depersonalisation disorder following the use of considerable amounts of cannabis for several weeks two years before. The symptoms decreased sharply after treatment with a serotonergic antidepressant. In cases of persistent or recurrent symptoms of depersonalisation, both psychiatric and somatic causes should be looked for. In cases of primary depersonalisation, the use of (soft) drugs should be considered in the differential diagnosis. Various forms of pharmaco- and psychotherapy seem to be able to reduce the symptoms. However, the effectiveness of no treatment has yet been proven.

Ned Tijdschr Geneeskd 2005;149:1058-61