Technieken voor het uitsluiten van urineweginfecties

Nienke Geerts en Volkher Scharnhorst

Techniques for excluding urinary tract infection

Urinary tract infections (UTIs) are the most common infections in both hospitalised patients and the general community. The gold standard for diagnosing an UTI is a positive bacterial culture. Unfortunately, bacterial culture is a time-consuming procedure, leading to a delay in proper treatment. This problem is often circumvented by diagnosing on clinical manifestation alone; however, diagnosis on symptoms alone will lead to an overestimation of the incidence of UTI. Employing a screening method to identify samples that do not have to be cultured has a positive effect on time-to-diagnosis, which is why screening methods to rule out UTI have been developed. The current screening methods and their pitfalls are described here, illustrated by two patient cases. A relatively new technique is also introduced: urine screening by flow cytometry. This overview updates the reader on how to exclude a urinary tract infection using screening methods.

Conflict of interest and financial support: none declared.