Farmacogenetisch testen op CYP450-enzymen

Ron H.N. van Schaik, Isa Houwink en Teun van Gelder

Pharmacogenetic testing of CYP450 enzymes

What to do with pharmacogenetic test results? In this article we discuss pharmacogenetic tests, with a focus on CYP450 enzymes. To illustrate the relevance of pharmacogenetics in clinical practice, we present two cases: firstly a 32-year-old patient with depression, who suffered from a broad range of side effects on different antidepressants; and secondly a 55-year-old patient with heart failure who presents his GP with a personal Pharmacogenetic Profile card.

Conflict of interest: none declared. Financial support: none declared.